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Testosterone Propionate Effects: There are a number of positive effects on the human body which are associated with the use of this anabolic steroid, including increased muscle mass, increased bone density, improved energy expenditure, and an increase in energy availability, all of which have been identified in animals [5, 14–16]. It is not surprising then to find that testosterone (3,4,5 HET) reduces the risk of cardiovascular and renal disease , and it also has the ability to preserve muscle mass and improve aerobic endurance during weight training in humans . These effects are due to an inhibition of lipogenesis and an increase in the rate of lipolysis from the liver, which is a mechanism used in both cells and tissues in order to convert ingested ingested fat to glucose . The anabolic effect of testosterone may have the same function in the body as anabolic steroids. However, unlike some other anabolic steroids, the anabolic effect of testosterone is not directly related to the steroid's effects on body weight or muscle mass. It may instead have more to do with increased energy expenditure, increased muscle mass, or an increase in brain energy metabolism and the resulting increase in exercise capacity [2, 5, 12–20]. Testosterone (3,4,5 HET) and Estradiol Testosterone is synthesized in the testes and is then transported to the ovaries where it is converted to estrogen under the action of the enzyme estrogen synthase (ES) that converts estrogen to androstenedione . At this point, there is no direct relation between testosterone and Estradiol, but it is very likely that testosterone and Estradiol work in tandem. This relationship could in part be explained by the fact that most Estradiol is synthesized in the ovaries and will be released in the body when the ovaries release an egg to the testicula, the duct of the ovaries that carries the eggs to the uterus . While there are certainly times when androgen is used in humans, it is not anabolic itself nor is it responsible for all male characteristics in testosterone-treated people . In contrast, some other anabolic steroids may directly affect Estradiol. One of these steroids is testosterone-enanthate, which is a variant of testosterone that also has similar androgenic effects and is known to be anabolic . Testosterone enanthate, also known as 5α-reductase, is a protein found in the testis that converts testosterone to androstenedione and thus, it can potentially be anabolic in humans. However, this protein Similar articles: